Bellahut Pentapeptide-18 Wrinkle Depth Reducer With Pentapeptide-18

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/Pentapeptide-18 peptide additive for mixing cream or serum
/Pentapeptide-18 peptide additive for mixing cream or serum
/Pentapeptide-18 peptide additive for mixing cream or serum
/Pentapeptide-18 peptide additive for mixing cream or serum
/Pentapeptide-18 peptide additive for mixing cream or serum
/Pentapeptide-18 peptide additive for mixing cream or serum
Pentapeptide-18 Wrinkle Depth Reducer
UPC#: 881874105523
Selected Size: 10 ml
Bellahut Price $25.95
Retail Price $51.90

Best Used For:Reduction of epression wrinkles.
Key Ingredients:Pentapeptide-18
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Often Purchased Together    

Trylagen™ Concentrate

Saccharide Isomerate

Expression Wrinkle Remover Complex aka Argirelox®
Add A Supplement For Better Results...


Caution: Do not apply undiluted peptides or additives directly onto your skin.  This product should be added to a formulation at the recommended usage rate. You can use Bellahut's premium cream or gel as your base for your formulation.

With the ability to reduce the depth of expression wrinkles up to 24.6% this key ingredient is a must have in any anti-aging cream. Add this to Bellahut's premium cream and combine with any number of our other premium peptides and make an extremely high quality cream that is tailored exactly for your needs.

Pentapeptide-18 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. It targets the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Acetyl hexapeptide-3.

Pentapeptide-18 is a peptide to reduce expression wrinkles that offers two main advantages:

  • A new and alternative in vitro mechanism to fight expression wrinkles.
  • An additive / synergistic effect to complement the action of Acetyl hexapeptide-3 and other peptides.

Pentapeptide-18's mechanism mimics in vitro the natural mechanism of enkephalins: it couples to the enkephalin receptor, on the outside of the nerve cells.  When Pentapeptide-18 couples to the receptor, a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability:  the nerve cell’s activity is “turned down” and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles can be diminished.


Incorporation: Pentapeptide-18 Peptide Solution should be incorporated at the end of the emulsion, at cool down, below 40C (104F). 
Suggested Usage: 3-10%

Appearance: Colorless, translucent solution
Solubility: Soluble in water

Long Term Storage:

Pentapeptide-18 should be stored in the original sealed containers protected from light in a clean and cool place and is best kept in the refrigerator. Long term storage recommended between 39.2° – 44.6°F (4° - 7°C). If stored properly, it should have a shelf life of up to 24 months.

INCI: Water [Aqua] (and) Glycerin (and) Pentapeptide-18



Mix with Bellahut's gel base or cream base and a combination of our other premium peptides to create your own custom treatment that is tailored to your needs. For best results use at a 3% to 10% concentration, keep in mind 10% is the maximum suggested concentration level for this product. 

This complex can create multiple products as below:

  • Wrinkle treatment product
  • Collagen boost product
  • Expression line treatment product


MSDS (Material Safety Data Sheet )

1. Product Identification

Product Name: Pentapeptide-18

INCI Name:Water [Aqua] (and) Glycerin (and) Pentapeptide-18

Composition/Information on Components: Gel containing a peptides

Hazardous Ingredients: /Preservatives: None


2. Physical and Chemical Properties

Solubility in Water: Dispersible

pH: 2-5


3. Stability and Reactivity

Chemical Stability: Stable


4. Handling and Storage

No particular precautions necessary. Long-term storage recommended

between 4 and 7°C.


5. Accidental Release Measures

Absorb on appropriate material. Wash with water and detergent. Flush

with water. Do not pour in pipes.


6. Exposure Controls & Personal Protection

Eye/ face Protection: Wear chemical goggles when there is a reasonable chance of eye contact.


7. Hazards Identification

Main Hazards: None


8. First Aid Measures

Eyes: Flush with water for 15 minutes, contact a physician if irritation persists

Inhalation: No data


Ingestion: Rinse one’s mouth. Give plenty of water.

9. Fire Fighting Measures

Extinguishing Media: Water, CO2


10. Toxicological Information

Patch test in humans (50%): well tolerated

RIPT (50%): non-sensitizing

HET CAM (50%): slight irritant

Systemic Tests

Neutral red test: slight cytotoxicity

AMES test: non-mutagenic


11. Disposal Considerations

Destruction/ Elimination: water dilution

Soiled packaging: wash with water- recyclable container

( Caution: there may be local regulation to be observed )

Important Notice:

This document is generated for the purpose of distributing health, safety, and environmental data. It is not a specification sheet nor should any displayed data be construed as a specification. The information on this MSDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, expressed or implied, regarding its correctness. Some information presented and conclusions drawn herein are from sources other than direct test data on the substance itself. The conditions or methods of handling, storage, use and disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage, or expense arising out of or in any way connected with handling, storage, use or disposal of this product. If the product is used as a component in another product, this MSDS information may not be applicable.

Distributed by Bellahut California
Made in U.S.A.

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